Author: Mahesh K R Kalikiri; Mohammad Rubayet Hasan; Faheem Mirza; Thabisile Xaba; Patrick Tang; Stephan Lorenz
Title: High-throughput extraction of SARS-CoV-2 RNA from nasopharyngeal swabs using solid-phase reverse immobilization beads Document date: 2020_4_11
ID: bx2xspbe_1
Snippet: In December 2019, the first reports of a new pathogenic virus causing severe respiratory illness emerged (1) . Early investigations determined that this new disease was caused by a novel coronavirus, SARS-CoV-2. Due to the rapid transmission and spread of the disease, the WHO declared this outbreak a global pandemic on 31 st January 2020 (2) . Because of the wide spectrum of presentations, from asymptomatic and subclinical infections to pneumonia.....
Document: In December 2019, the first reports of a new pathogenic virus causing severe respiratory illness emerged (1) . Early investigations determined that this new disease was caused by a novel coronavirus, SARS-CoV-2. Due to the rapid transmission and spread of the disease, the WHO declared this outbreak a global pandemic on 31 st January 2020 (2) . Because of the wide spectrum of presentations, from asymptomatic and subclinical infections to pneumonia and acute respiratory distress syndrome, many of which resemble other common respiratory infections, laboratory testing is essential for establishing the diagnosis of COVID-19. Once infected individuals are identified through laboratory testing, they can be isolated and managed appropriately, along with identification and quarantine of their contacts. The increased demand for laboratory testing has led to global shortages of all the required supplies, from personal protective equipment such as N95 masks, to swabs, and even the reagents required for viral RNA extraction.
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