Author: Mateo-Urdiales, Alberto; Spila Alegiani, Stefania; Fabiani, Massimo; Pezzotti, Patrizio; Filia, Antonietta; Massari, Marco; Riccardo, Flavia; Tallon, Marco; Proietti, Valeria; Del Manso, Martina; Puopolo, Maria; Spuri, Matteo; Morciano, Cristina; D’Ancona, Fortunato (Paolo); Da Cas, Roberto; Battilomo, Serena; Bella, Antonino; Menniti-Ippolito, Francesca
Title: Risk of SARS-CoV-2 infection and subsequent hospital admission and death at different time intervals since first dose of COVID-19 vaccine administration, Italy, 27 December 2020 to mid-April 2021 Cord-id: pqifgzp8 Document date: 2021_6_24
ID: pqifgzp8
Snippet: To assess the real-world impact of vaccines on COVID-19 related outcomes, we analysed data from over 7 million recipients of at least one COVID-19 vaccine dose in Italy. Taking 0–14 days post-first dose as reference, the SARS-CoV-2 infection risk subsequently decreased, reaching a reduction by 78% (incidence rate ratios (IRR): 0.22; 95% CI: 0.21–0.24) 43–49 days post-first dose. Similarly, hospitalisation and death risks decreased, with 89% (IRR: 0.11; 95% CI: 0.09–0.15) and 93% (IRR: 0.
Document: To assess the real-world impact of vaccines on COVID-19 related outcomes, we analysed data from over 7 million recipients of at least one COVID-19 vaccine dose in Italy. Taking 0–14 days post-first dose as reference, the SARS-CoV-2 infection risk subsequently decreased, reaching a reduction by 78% (incidence rate ratios (IRR): 0.22; 95% CI: 0.21–0.24) 43–49 days post-first dose. Similarly, hospitalisation and death risks decreased, with 89% (IRR: 0.11; 95% CI: 0.09–0.15) and 93% (IRR: 0.07; 95% CI: 0.04–0.11) reductions 36–42 days post-first dose. Our results support ongoing vaccination campaigns.
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