Author: David M Rubin; Neil T Stacey; Tonderayi Matambo; Diane Hildebrandt
Title: Oxygen transfer characteristics of a hollow fiber dialyser: toward possible repurposing of dialysers as blood oxygenators in the context of constrained availability of respiratory support Document date: 2020_4_11
ID: 4igpae7w_14
Snippet: By comparison with Hb-containing blood, the potential uptake of oxygen by water is only a small fraction of the percentage of uptake by blood due to the low solubility of the oxygen and the small driving force. For example, 500 ml of water with an inlet oxygen concentration in equilibrium with air at 1 atm can only take up 0.0043 g of oxygen to achieve an outlet concentration of 25 mmHg. As we have used water as a blood substitute in these experi.....
Document: By comparison with Hb-containing blood, the potential uptake of oxygen by water is only a small fraction of the percentage of uptake by blood due to the low solubility of the oxygen and the small driving force. For example, 500 ml of water with an inlet oxygen concentration in equilibrium with air at 1 atm can only take up 0.0043 g of oxygen to achieve an outlet concentration of 25 mmHg. As we have used water as a blood substitute in these experiments, this will become relevant in the estimation of the performance of the system with blood.
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