Author: Lin Fu; Jun Fei; Shen Xu; Hui-Xian Xiang; Ying Xiang; Zhu-Xia Tan; Meng-Die Li; Fang-Fang Liu; Ying Li; Ming-Feng Han; Xiu-Yong Li; Hui Zhao; De-Xiang Xu
Title: Acute liver injury and its association with death risk of patients with COVID-19: a hospital-based prospective case-cohort study Document date: 2020_4_6
ID: 5gbjdr0u_39
Snippet: In summary, this study aimed to investigate SARS-CoV-2-induced ALI among 355 COVID-19 patients from two hospitals. Our results revealed that SARS-CoV-2-induced ALI was more common in critically ill patients. In addition, male elderly COVID-19 patients with diabetes mellitus and lymphopenia were more susceptible to ALI. We provide evidence that ALI at the early stage elevates death risk of COVID-19 patients. Importantly, SARS-CoV-2-induced ALI has.....
Document: In summary, this study aimed to investigate SARS-CoV-2-induced ALI among 355 COVID-19 patients from two hospitals. Our results revealed that SARS-CoV-2-induced ALI was more common in critically ill patients. In addition, male elderly COVID-19 patients with diabetes mellitus and lymphopenia were more susceptible to ALI. We provide evidence that ALI at the early stage elevates death risk of COVID-19 patients. Importantly, SARS-CoV-2-induced ALI has not recovered completely 14 days after discharge. Therefore, it is necessary to further evaluate whether SARS-CoV-2 infection causes permanent liver injury.
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