Preliminary study to identify severe from moderate cases of COVID-19 using NLR&RDW-SD combination parameter

changzheng wang; Chengbin Li

Meanwhile, we used the cut-off values of the best single-parameter NLR and the combined parameter NLR&RDW-SD as the judgment thresholds and listed the fourfold tables (Table 5 and Table 6 ) to calculate the other diagnostic items, it was found that the combined parameter NLR&RDW-SD had better diagnostic performance, with a diagnostic accuracy rate of 85.7%, and better predictive value and likelihood ratio than the single parameter NLR. [17] . Although the current epidemiological situation shows that the SARS-CoV-2 is more contagious than SARS-CoV and MERS-CoV, clustering of outbreak among people, but its lethality is less severe [35] [36] [37] [38] [39] . outbreak also had a high mortality rate in the early stage in some areas. The first 41 confirmed infection cases admitted to hospitals in Wuhan from December 16, 2019 to January 2, 2020 showed that the COVID-19 patients had a 15% mortality rate at the beginning of the outbreak, and 32% of patients required ICU monitoring and treatment [11] . As of the latest data published by the WHO [19] . Therefore, many experts remind us that SARS-CoV-2 may coexist with humans for a long time [35] and the potential infection risk needs special attention with the increase in the number of asymptomatic infections [18] . Marc Lipsitch, a professor of epidemiology at Harvard University, predicted that the SARS-CoV-2 would infect 40% -70% of people worldwide by 2020 [34] . Therefore, tracking and screening . CC-BY-NC-ND 4.0 International license It is made available under a is the author/funder, who has granted medRxiv a license to display the preprint in perpetuity.