Study of the role of an infectious factor in the development of stroke in children. Results of a 5-year retrospective analysis

Ivanova, A. A.; Shamsheva, O. V.; Shchederkina, I. O.

Objective: Determine the role of infectious diseases in the development of strokes in children and to identify risk groups for its progression. Materials and Methods: A retrospective analysis of 660 case histories of children aged 1 months to 18 years old, hospitalized in Morozov Children's City Clinical Hospital with stroke in the period from 2016 to July 2020 was carried out. Results. An infectious disease or fever 4 weeks before stroke is diagnosed in 78 (12%) cases. Infections more often act as a stroke trigger in children under 7 years old (28% in children under one year old). The incidence of strokes against a background of a bacterial infection is higher than against a background of a viral infection (47% versus 35%). Among bacterial infections, meningitis (35%), otitis media (24%), pneumonia (18%) prevailed. With a viral infection, viruses of Herpes are more common (44%), as well as respiratory viruses (37%). Two cases of cerebrovascular accident were revealed in children who have undergone a new coronavirus infection SARS-CoV-2 (7%). Among the types of stroke, with bacterial infection, sinus thrombosis was more common (50%), among viral infection, the most common was ischemic stroke (60%). The presence of an additional risk factor was revealed in 72%, most often these were prothrombotic conditions (35%).