Author: Mouton, William; Compagnon, Christelle; Saker, Kahina; Daniel, Soizic; Djebali, Sophia; Lacoux, Xavier; Pozzetto, Bruno; Oriol, Guy; Laubreton, Daphné; Prieux, Margaux; Fassier, Jeanâ€Baptiste; Guibert, Nicolas; Massardierâ€Pilonchéry, Amélie; Alfaiate, Dulce; Berthier, Franck; Walzer, Thierry; Marvel, Jacqueline; Brengelâ€Pesce, Karen; Trouillerâ€Assant, Sophie
Title: Specific detection of memory Tâ€cells in COVIDâ€19 patients using standardized wholeâ€blood Interferon gammarelease assay Cord-id: teirfbcn Document date: 2021_9_6
ID: teirfbcn
Snippet: Antigenâ€specific Tâ€cells are essential for protective immunity against SARSâ€CoVâ€2. We set up a semiâ€automated wholeâ€blood Interferonâ€gamma release assay (WB IGRA) to monitor the Tâ€cell response after stimulation with SARSâ€CoVâ€2 peptide pools. We report that the WB IGRA is complementary to serological assays to assess SARSâ€CoVâ€2 immunity. [Image: see text]
Document: Antigenâ€specific Tâ€cells are essential for protective immunity against SARSâ€CoVâ€2. We set up a semiâ€automated wholeâ€blood Interferonâ€gamma release assay (WB IGRA) to monitor the Tâ€cell response after stimulation with SARSâ€CoVâ€2 peptide pools. We report that the WB IGRA is complementary to serological assays to assess SARSâ€CoVâ€2 immunity. [Image: see text]
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