MO197 KIDNEY FUNCTION AT THE EARLY ON ADMISSION HAS NO CORRELATED WITH DISEASE SEVERITY AND MORTALITY IN COVID-19 PATIENTS WHO ARE TREATED IN ISOLATION ROOM OF MUHAMMADIYAH HOSPITAL PALANGKARAYA INDONESIA

Tanod, Darryl Virgiawan

BACKGROUND AND AIMS: Covid-19 easily to infected and spread between person to person with different mortality rates. Affected by several factors, including the comorbid factors that are different in each patients . One of the comorbid factors currently being discussed is the function of the kidneys which can affect the severity of disease and mortality in people with Covid-19. The purpose of this study was to determine whether early kidney function in Covid-19 patients who were treated in hospital isolation rooms Muhammadiyah Palangkaraya has an effect on degrees of severity and mortality. METHOD: This study was a retrospective observational study conducted at a Covid-19 referral hospital. The data were taken from the electronic health records of the hospital from July – December 2020. A 38 male and female patients, with mild and severe disease. Kidney function is known by calculating the eGFR value at the time of patients initial admission using serum creatinin through venous blood test then calculated using the formula CKD-EPI calculator. Independent Sample T-test statistical was perform to see the correlation between eGFR and the degree of severity and mortality of Covid-19 patients. RESULTS: In this study, a total of 38 patients consist of 15 (39.47%) men and 23 (60.52%) women who suffered from mild Covid-19 were 11 (28.94%) people, and severe 27 (71.05%) people. There were 5 patients who died (13.15%) and 33 (86.84%) who were alive. It was found that there was no correlation between the patient's baseline eGFR and the patient's mortality rate (p = 0.98), while the eGFR with the degree of severity was also not correlated (p = 0.89). CONCLUSION: In this study, there was no correlation between initial kidney function in admission Covid-19 patients with the severity of Covid-19 and mortality rates. Other comorbid factors apart from renal function, early management and optimal treatment are thought to affect severity and mortality of these patients regardless of initial renal function at the time the patient was treated.