The indirect impact of COVID-19 large-scale containment measures on the incidence of community-acquired pneumonia in the elderly: a region-wide population-based study in Tuscany, Italy

Lastrucci, Vieri; Bonaccorsi, Guglielmo; Forni, Silvia; D'Arienzo, Sara; Bachini, Letizia; Paoli, Sonia; Lorini, Chiara; Gemmi, Fabrizio

OBJECTIVE: : to evaluate the indirect effect of COVID-19 large-scale containment measures on the incidence of community-acquired pneumonia (CAP) in the elderly during the first epidemic wave of COVID-19 in Tuscany, Italy. METHODS: : a population based study was carried out on data from the Tuscany healthcare system. The outcome measures were: hospitalization rate for CAP, severity of CAP hospitalizations, and outpatient consumptions of antibacterials for CAP in people aged 65 years and older. Outcome comparisons between corresponding periods of the 2020 and previous years were made. RESULTS: : Compared with the average of the corresponding periods of the previous three years, significant reductions in the weekly hospitalization rates for CAP were observed starting from the week in which the national containment measures were imposed until the end of the first wave of COVID-19 in July. All the antibacterial classes for CAP showed a significant decrease in their outpatient consumptions during the COVID-19 epidemic period. CONCLUSIONS: : The implementation of large-scale COVID-19 containment measures likely reduced the incidence of CAP in the elderly during the first wave of COVID-19 pandemic. Taking into account this indirect impact of pandemic containment measures on respiratory tract infections may improve the planning of health services during a pandemic.