Author: Lucchini, Giovanna; Furness, Caroline; Lawson, Sarah; Gibson, Brenda; Wynn, Robert; Slatter, Mary; Shillitoe, Ben; James, Beki; Carpenter, Ben; Hough, Rachael; Amrolia, Persis; de la Fuente, Josu
Title: COVIDâ€19 infection in paediatric recipients of allogeneic stem cell transplantation: the UK experience Cord-id: qma53mvv Document date: 2021_6_20
ID: qma53mvv
Snippet: Data defining the clinical course of COVID19 infection in HSCT recipients are limited. We assessed the impact of COVID19 on paediatric HSCT recipients in the UK between February and June 2020. Nine patients developed COVID 19 proven infection at a median time of 62 days post-transplant. Presenting symptoms were mostly fevers and cough. One case had a severe course, requiring non-invasive ventilation and receiving dexamethasone, tocilizumab, remdesivir. No patients died from COVID19. Two patients
Document: Data defining the clinical course of COVID19 infection in HSCT recipients are limited. We assessed the impact of COVID19 on paediatric HSCT recipients in the UK between February and June 2020. Nine patients developed COVID 19 proven infection at a median time of 62 days post-transplant. Presenting symptoms were mostly fevers and cough. One case had a severe course, requiring non-invasive ventilation and receiving dexamethasone, tocilizumab, remdesivir. No patients died from COVID19. Two patients developed significant complications following COVID19 disease. Our data describe a relative mild infection course in HSCT recipients but highlight potential infectious triggered complications.
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