Author: Ashish Goyal; E. Fabian Cardozo-Ojeda; Joshua T Schiffer
Title: Potency and timing of antiviral therapy as determinants of duration of SARS CoV-2 shedding and intensity of inflammatory response Document date: 2020_4_14
ID: d7stppv5_8
Snippet: Our model reproduced viral load kinetics in all 25 participants (Fig. 1b) . In certain cases, the model only fit to available data from the later stages of shedding, whereas it recapitulated the entirety of viral expansion, peak and decelerating clearance for several study participants (S5, S14, S18, G1, G2, G5, G7). In keeping with observations from a recent clinical trial (15) , low level shedding continued past 20 days for some German particip.....
Document: Our model reproduced viral load kinetics in all 25 participants (Fig. 1b) . In certain cases, the model only fit to available data from the later stages of shedding, whereas it recapitulated the entirety of viral expansion, peak and decelerating clearance for several study participants (S5, S14, S18, G1, G2, G5, G7). In keeping with observations from a recent clinical trial (15) , low level shedding continued past 20 days for some German participants (G1, G2, G3, G5, G6), whereas viral elimination occurred in the remaining infected people.
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