Author: Rezaeitalab, Fariborz; Jamehdar, Saeid Amel; Sepehrinezhad, Ali; Rashidnezhad, Azra; Moradi, Fereydoun; Sadat Esmaeli Fard, Fateme; Hasanzadeh, Sepideh; Etezad Razavi, Mohammad; Gorji, Ali; Sahab Negah, Sajad
Title: Detection of SARS-coronavirus-2 in the central nervous system of patients with severe acute respiratory syndrome and seizures Cord-id: qv7tbqpf Document date: 2021_3_1
ID: qv7tbqpf
Snippet: This study was designed to evaluate whether severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can directly target the central nervous system (CNS). We present four patients suffering from the loss of consciousness and seizure during the clinical course of COVID-19 infection. In addition to positive nasopharyngeal swab tests, SARS-CoV-2 has been detected in their cerebrospinal fluid. This report indicates the neuroinvasive potential of SARS-CoV-2, suggesting the ability of this virus t
Document: This study was designed to evaluate whether severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) can directly target the central nervous system (CNS). We present four patients suffering from the loss of consciousness and seizure during the clinical course of COVID-19 infection. In addition to positive nasopharyngeal swab tests, SARS-CoV-2 has been detected in their cerebrospinal fluid. This report indicates the neuroinvasive potential of SARS-CoV-2, suggesting the ability of this virus to spread from the respiratory tract to the CNS. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s13365-020-00938-w.
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