Selected article for: "brain tissue and case report"

Author: Lima, Behnam Safarpour; Khorasani, Negar Mohammadi; Aghamiri, Seyed Hossein; Omidi, Fatemeh; Nilipour, Yalda
Title: Neurological Complications of COVID-19: A Rare Case of Bilateral Blindness
  • Cord-id: trh3fwga
  • Document date: 2021_7_19
  • ID: trh3fwga
    Snippet: BACKGROUND: There are growing reports of the neurologic involvement among the patients with COVID-19. Headache, confusion, and anosmia following olfactory nerve disruption are the most prevalent presentation of the neurologic involvement related to COVID-19. However, small numbers of the central nervous system (CNS) involvement have been reported. CASE REPORT: A 49-year-old male was referred to our hospital with an abrupt vision loss. Three weeks earlier he was admitted to hospital based on his
    Document: BACKGROUND: There are growing reports of the neurologic involvement among the patients with COVID-19. Headache, confusion, and anosmia following olfactory nerve disruption are the most prevalent presentation of the neurologic involvement related to COVID-19. However, small numbers of the central nervous system (CNS) involvement have been reported. CASE REPORT: A 49-year-old male was referred to our hospital with an abrupt vision loss. Three weeks earlier he was admitted to hospital based on his respiratory symptoms and was diagnosed with COVID-19 infection. Initial Brain MRI indicated diffuse restricted bilateral foci in both parietal and occipital lobes in favor of acute infarction. Diffuse Weighted Imaging (DWI) demonstrated restricted bilateral hyperintense signals in parietal and occipital region. Occipital cortex biopsy showed brain tissue with focal infiltration of foamy macrophages mixed with reactive astrocytes and no plasma cell infiltration. Considering all the evidence, post-COVID-19 encephalitis diagnosis was considered for the patient, and methyl prednisolone pulse-therapy and intravenous immunoglobulin (IVIg) was initiated. Why should an emergency physician be aware of this? Although there are growing reports of the neurologic involvement among the patients, blindness can rarely be observed as a complication of post-COVID-19 encephalitis. To our knowledge this is the first case of post-COVID-19 encephalitis which presented with bilateral vision loss primarily. This case may raise physicians’ awareness of neurological complications of COVID-19.

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