Author: Chong Lei; Binxiao Su; Hailong Dong; Andrea Bellavia; Raffaele Di Fenza; Bijan Safaee Fakhr; Stefano Gianni; Luigi Giuseppe Grassi; Robert Kacmarek; Caio Cesar Araujo Morais; Riccardo Pinciroli; Emanuele Vassena; Lorenzo Berra
Title: Protocol of a randomized controlled trial testing inhaled Nitric Oxide in mechanically ventilated patients with severe acute respiratory syndrome in COVID-19 (SARS-CoV-2). Document date: 2020_3_13
ID: e99athff_22
Snippet: Sample size. We hypothesize that NO gas therapy leads to an improvement of oxygenation due to amelioration of ventilation perfusion matching in patients affected with SARS-CoV2. A difference of 20% in PaO2/FiO2 ratio between the two groups at 48 hours from enrollment is considered to be clinically relevant. Available data on oxygenation in SARS-CoV and SARS-. CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who ha.....
Document: Sample size. We hypothesize that NO gas therapy leads to an improvement of oxygenation due to amelioration of ventilation perfusion matching in patients affected with SARS-CoV2. A difference of 20% in PaO2/FiO2 ratio between the two groups at 48 hours from enrollment is considered to be clinically relevant. Available data on oxygenation in SARS-CoV and SARS-. CC-BY-NC-ND 4.0 International license It is made available under a author/funder, who has granted medRxiv a license to display the preprint in perpetuity.
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