Acute Myocardial Injury of Patients with Coronavirus Disease 2019

Huayan Xu; Keke Hou; Hong Xu; Zhenlin Li; Huizhu Chen; Na Zhang; Rong Xu; Hang Fu; Ran Sun; Lingyi Wen; Linjun Xie; Hui Liu; Kun Zhang; Joseph B Selvanayagam; Chuan Fu; Shihua Zhao; Zhigang Yang; Ming Yang; Yingkun Guo

Meanwhile, there were some differences in echo and ECG findings ( Table 2) . Of all the COVID-19 patients, 45.28% (n=24) patients exhibited echo abnormalities. Echo abnormalities more frequently occurred in the AMI group and included left atrial enlargement (n=2), left ventricular (LV) enlargement (n=2), LV diastolic dysfunction (n=3), mitral valve regurgitation (n=2), triple valve regurgitation (n=1), and aortic valve regurgitation (n=1). Three AMI patients had LV wall thickening. It is noteworthy that non-definite AMI patients with cardiac marker abnormalities also had high frequency of echo abnormalities (n=15, 62.50%), with 11(45.83%) of them having more than two of the abovementioned echo abnormalities. The most frequent echo abnormality in the cardiac marker abnormalities group was LV diastolic dysfunction (n=14, 58.33%). Table 3 , 11 (20.75%) COIVD-19 patients had ECG abnormalities, including all the AMI patients and five (20.83%) non-definite AMI patients with cardiac marker abnormalities. Five of the AMI patients had more than two kinds of ECG abnormalities including atrioventricular block (n=2), ST-T/Q curve abnormalities (n=2), and arrhythmia (n=3); furthermore, ST-T/Q curve abnormalities (n=5, 20.83%) and arrhythmia (n=1, 4.27%) were the main abnormalities in patients with cardiac marker abnormalities. None of the patients without cardiac marker abnormalities exhibited ECG abnormalities.