Acute Myocardial Injury of Patients with Coronavirus Disease 2019

Huayan Xu; Keke Hou; Hong Xu; Zhenlin Li; Huizhu Chen; Na Zhang; Rong Xu; Hang Fu; Ran Sun; Lingyi Wen; Linjun Xie; Hui Liu; Kun Zhang; Joseph B Selvanayagam; Chuan Fu; Shihua Zhao; Zhigang Yang; Ming Yang; Yingkun Guo

The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.05.20031591 doi: medRxiv preprint Table 3 shows the main management strategies, comorbid conditions, and clinical outcomes of all the COVID-19 patients. In the AMI group, in addition to antiviral and antibiotic therapies, cardioprotective medications such as amiodarone and cedilla were used by four patients to improve the cardiac function. However, the non-definite AMI patients with and without cardiac markers abnormalities did not use cardioprotective medication. All the 53 patients were administered nasal cannula oxygen therapy during admission for respiratory support; non-invasive ventilation or high-flow nasal cannula oxygen therapy was performed for five AMI and three non-definite AMI patients with cardiac marker abnormalities. Notably, in the AMI group, invasive mechanical ventilation was used in three patients and ECMO in one patient due to extremely severe ARDS.