Selected article for: "curve analysis and melting curve"

Author: Truffot, Aurélie; Andréani, Julien; Le Maréchal, Marion; Caporossi, Alban; Epaulard, Olivier; Germi, Raphaele; Poignard, Pascal; Larrat, Sylvie
Title: SARS-CoV-2 Variants in Immunocompromised Patient Given Antibody Monotherapy
  • Cord-id: uhxol85c
  • Document date: 2021_10_25
  • ID: uhxol85c
    Snippet: A 72-year-old immunocompromised man infected with severe acute respiratory syndrome coronavirus 2 received bamlanivimab monotherapy. Viral evolution was monitored in nasopharyngeal and blood samples by melting curve analysis of single-nucleotide polymorphisms and whole-genome sequencing. Rapid emergence of spike receptor binding domain mutations was found, associated with a compartmentalization of viral populations.
    Document: A 72-year-old immunocompromised man infected with severe acute respiratory syndrome coronavirus 2 received bamlanivimab monotherapy. Viral evolution was monitored in nasopharyngeal and blood samples by melting curve analysis of single-nucleotide polymorphisms and whole-genome sequencing. Rapid emergence of spike receptor binding domain mutations was found, associated with a compartmentalization of viral populations.

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