Acute Myocardial Injury of Patients with Coronavirus Disease 2019

Huayan Xu; Keke Hou; Hong Xu; Zhenlin Li; Huizhu Chen; Na Zhang; Rong Xu; Hang Fu; Ran Sun; Lingyi Wen; Linjun Xie; Hui Liu; Kun Zhang; Joseph B Selvanayagam; Chuan Fu; Shihua Zhao; Zhigang Yang; Ming Yang; Yingkun Guo

Our study has some limitations. First, this is a modest-size case series of hospitalized COVID-19 patients; more standardized data from a larger cohort would beneficial for further determining the clinical characteristics. Second, our data showed the clinical characteristics of AMI induced by COVID-19, including the clinical presentations, electrophysiological abnormality, myocardial enzyme and myocardial injury marker levels, and cardiac dysfunction and enlargement. However, the tissue characteristics in myocardial damage (i.e., edema, fibrosis, and microcirculation disorder) should be further demonstrated via cardiac magnetic resonance imaging examination as far as possible under the premise of controlling transmission. Finally, most of the COVID-19 patients with AMI had severe or critically severe NCP and high fatality rate, but long-term follow-up should be performed to determine adverse cardiac All rights reserved. No reuse allowed without permission. author/funder, who has granted medRxiv a license to display the preprint in perpetuity.