Author: Colivicchi, Furio; Di Fusco, Stefania Angela; Scicchitano, Pietro; Caldarola, Pasquale; Murrone, Adriano; Valente, Serafina; Urbinati, Stefano; Roncon, Loris; Amodeo, Vincenzo; Aspromonte, Nadia; Cipriani, Manlio; Domenicucci, Stefano; Francese, Giuseppina Maura; Imazio, Massimo; Scotto di Uccio, Fortunato; Di Lenarda, Andrea; Gulizia, Michele Massimo; Gabrielli, Domenico
Title: Updated clinical evidence and place in therapy of bempedoic acid for hypercholesterolemia: ANMCO position paper. Cord-id: v18y5f1d Document date: 2020_8_24
ID: v18y5f1d
Snippet: : The central role of high low-density lipoprotein cholesterol levels in atherosclerotic cardiovascular disease has led to research focused on lipid-lowering agents for cardiovascular risk reduction. Bempedoic acid is an emerging treatment for hypercholesterolemia that has recently been approved for marketing in the United States and Europe. This review focuses on its mechanism of action and summarizes the main preclinical study findings. Furthermore, we report the clinical evidence supporting a
Document: : The central role of high low-density lipoprotein cholesterol levels in atherosclerotic cardiovascular disease has led to research focused on lipid-lowering agents for cardiovascular risk reduction. Bempedoic acid is an emerging treatment for hypercholesterolemia that has recently been approved for marketing in the United States and Europe. This review focuses on its mechanism of action and summarizes the main preclinical study findings. Furthermore, we report the clinical evidence supporting and guiding its use in hypercholesterolemia management.
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