Author: Zheng Zhang; Sifan Ye; Aiping Wu; Taijiao Jiang; Yousong Peng
Title: Prediction of receptorome for human-infecting virome Document date: 2020_2_28
ID: 9ruhvpbv_37
Snippet: Then, we further investigated the prediction of virus-receptor interactions. In previous study, Lasso et al. predicted 282, 528 pairs of PPIs between human and 1,001 human-infecting viruses (Lasso et al., 2019) . Based on their study, 9,395 pairs of PPIs between 718 viral RBPs from 693 human-infecting viruses, and 314 human cell membrane proteins were extracted for further analysis (see Table S2 ). A viral RBP was predicted to interact with 1 to .....
Document: Then, we further investigated the prediction of virus-receptor interactions. In previous study, Lasso et al. predicted 282, 528 pairs of PPIs between human and 1,001 human-infecting viruses (Lasso et al., 2019) . Based on their study, 9,395 pairs of PPIs between 718 viral RBPs from 693 human-infecting viruses, and 314 human cell membrane proteins were extracted for further analysis (see Table S2 ). A viral RBP was predicted to interact with 1 to 65 human cell membrane proteins, with a median of 10. For each viral RBP, the RBP-interacting cell membrane proteins were ranked by the score provided by the RF model to select the most likely receptor (Table S2) .
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