Author: Krueger, Mariana Braatz; Montenegro, Raquel Carvalho; de Araújo Coimbra, Pablo Picasso; de Queiroz Lemos, Luanna; Fiorenza, Regiane Martins; da Silva Fernandes, Carla Jéssica; Pessoa, Mariana Santos Leite; Rodrigues, CleonÃsio Leite; da Cruz, Camilla Gomes; de Araújo Verdiano, Verlene; de Carvalho Araújo, Fernanda Montenegro; Braga-Neto, Pedro; Sobreira-Neto, Manoel Alves
Title: A wide spectrum of neurological manifestations in pediatrics patients with the COVID-19 infection: a case series Cord-id: qz6y4ozo Document date: 2021_8_26
ID: qz6y4ozo
Snippet: Neurological symptoms in COVID-19 patients can also be found in the pediatric population, but they are usually described as mild symptoms. Herein, we described a case series of four pediatric patients with severe and highly heterogeneous central and peripheral nervous system manifestations. The objective was to report neurological manifestations of COVID-19 in children and adolescents. The design is case series. The participants are four children and adolescents with confirmed COVID-19. The main
Document: Neurological symptoms in COVID-19 patients can also be found in the pediatric population, but they are usually described as mild symptoms. Herein, we described a case series of four pediatric patients with severe and highly heterogeneous central and peripheral nervous system manifestations. The objective was to report neurological manifestations of COVID-19 in children and adolescents. The design is case series. The participants are four children and adolescents with confirmed COVID-19. The main outcome and measures are as follows: Clinical data were gathered from electronic medical records, and data of all neurologic symptoms were checked by a trained neurologist. We reported four pediatric patients with COVID-19 and different neurologic symptoms. Case 1 was a 16-year-old girl with a sensory and motor polyradiculopathy with RT-qPCR for COVID-19 and dengue both detected in CSF that improved after appropriate treatment. Case 2 was a 15-year-old boy with Guillain–Barre syndrome and had good response after using human immunoglobulin. Case 3 was a 5-year-old girl with acute intracranial hypertension that improved after going through lumbar puncture and using acetazolamide. Case 4 was a 2-month-old male infant with focal epileptic seizures that recovered after antiepileptic treatment. We highlight the need to consider different neurologic manifestations as part of the COVID-19 clinical spectrum.
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