Author: Melchjorsen, Jesper; Sørensen, Louise N.; Paludan, Søren R.
Title: Expression and function of chemokines during viral infections: from molecular mechanisms to in vivo function Cord-id: sfhws9td Document date: 2003_6_16
ID: sfhws9td
Snippet: Recruitment and activation of leukocytes are important for elimination of microbes, including viruses, from infected areas. Chemokines constitute a group of bioactive peptides that regulate leukocyte migration and also contribute to activation of these cells. Chemokines are essential mediators of inflammation and important for control of viral infections. The profile of chemokine expression contributes to shaping the immune response during viral infection, whereas viral subversion of the chemoki
Document: Recruitment and activation of leukocytes are important for elimination of microbes, including viruses, from infected areas. Chemokines constitute a group of bioactive peptides that regulate leukocyte migration and also contribute to activation of these cells. Chemokines are essential mediators of inflammation and important for control of viral infections. The profile of chemokine expression contributes to shaping the immune response during viral infection, whereas viral subversion of the chemokine system allows the virus to evade antiviral activities of the host. In this review, we discuss the role of chemokines in hostâ€defense against virus infections, and we also look deeper into the virusâ€cell interactions that trigger chemokine expression as well as the cellular signaling cascades involved.
Search related documents:
Co phrase search for related documents- Try single phrases listed below for: 1
Co phrase search for related documents, hyperlinks ordered by date