Selected article for: "dynamic range and IgG detection"

Author: Xiaotian Tan; Cory Lin; Jie Zhang; Maung Kyaw Khaing Oo; Xudong Fan
Title: Rapid and quantitative detection of COVID-19 markers in micro-liter sized samples
  • Document date: 2020_4_22
  • ID: 0tdfvlqd_46
    Snippet: We will continue to optimize our assays in multiple aspects. For IgG detection, we will investigate more humanized or patient-derived SARS-CoV-2 S1 antibodies to identify optimal calibrators with a high binding affinity and a large linear dynamic range. The differences in the antibodies' affinity against monomeric S1 (most commonly used in antibody and vaccine development) and trimeric S1 (the natural conformation of S1 on SARS-CoV-2 virus) can a.....
    Document: We will continue to optimize our assays in multiple aspects. For IgG detection, we will investigate more humanized or patient-derived SARS-CoV-2 S1 antibodies to identify optimal calibrators with a high binding affinity and a large linear dynamic range. The differences in the antibodies' affinity against monomeric S1 (most commonly used in antibody and vaccine development) and trimeric S1 (the natural conformation of S1 on SARS-CoV-2 virus) can also be author/funder. All rights reserved. No reuse allowed without permission.

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