Author: Gürbüz, Gürkan; Edizer, Selvinaz; Yılmaz, Ünsal; Ünalp, Aycan
Title: The Importance of Thiopurine S-Methyltransferase Gene Analysis Before Azathioprine Therapy. Cord-id: u2cks16y Document date: 2020_6_22
ID: u2cks16y
Snippet: Neuromyelitis optica is an inflammatory central nervous system syndrome associated with serum aquaporin-4 IgG antibody. Optic nerve and spinal cord involvement is typical. We report a 9-year-old girl with a diagnosis of neuromyelitis optica, who developed azathioprine-induced pancytopenia that was subsequently found to be caused by thiopurine-methyltransferase mutation.
Document: Neuromyelitis optica is an inflammatory central nervous system syndrome associated with serum aquaporin-4 IgG antibody. Optic nerve and spinal cord involvement is typical. We report a 9-year-old girl with a diagnosis of neuromyelitis optica, who developed azathioprine-induced pancytopenia that was subsequently found to be caused by thiopurine-methyltransferase mutation.
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