Selected article for: "immune response and SARS cov"
Author: Rosanna Asselta; Elvezia Maria Paraboschi; Alberto Mantovani; Stefano Duga
Title: ACE2 and TMPRSS2 variants and expression as candidates to sex and country differences in COVID-19 severity in Italy
  • Document date: 2020_4_2
    • ID: hrottr01_2
    Snippet: https://www.epicentro.iss.it/coronavirus/), a feature shared with the 2003 SARS epidemic and MERS. [3] [4] [5] Indeed, while men and women have similar susceptibility to both SARS-CoV-2 and SARS-CoV, men are more prone to have higher severity and mortality, independently of age. 3 Among the many possible factors impacting on sexrelated differences in disease manifestations, including the fact that females are known to mount a stronger immune resp.....
    Document: https://www.epicentro.iss.it/coronavirus/), a feature shared with the 2003 SARS epidemic and MERS. [3] [4] [5] Indeed, while men and women have similar susceptibility to both SARS-CoV-2 and SARS-CoV, men are more prone to have higher severity and mortality, independently of age. 3 Among the many possible factors impacting on sexrelated differences in disease manifestations, including the fact that females are known to mount a stronger immune response to viral infections compared to males due to more robust humoral and cellular immune responses, 6 we decided to center our attention on possible genetic components, with a particular focus on the Italian population.

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