MO872 INFLUENCE OF SARS-COV-2 INFECTION ON MORTALITY IN PATIENTS UNDER RENAL SUBSTITUTE TREATMENT

Ferrer García, Guillermo; Piccone Saponara, Luis Guillermo; Sanchez Escudero, Patricia; Castro Fernández, Maria Paz; Uribe Heredia, Nancy Giovanna; Olazo Gutierrez, Eliana; Carreño Parrilla, Agustín; Anaya Fernández, Sara; García Conejo, Gloria; Ugarte Camara, Marina; Vozmediano Poyatos, Carmen

BACKGROUND AND AIMS: Dialysis patients constitute a risk group for coronavirus infection due to their immunosuppressed condition, with the increased risk of morbidity and mortality that this entails. We analyzed the factors associated with mortality from coronavirus infection in a cohort of patients undergoing renal replacement therapy at our center. METHOD: Transversal study. We included patients in renal replacement therapy (RRT) in our center. Demographic variables (age, sex), associated comorbidity, RRT technique, clinical and laboratory parameters were collected. Statistical analysis with SPSS 25.0. Categorical variables are expressed in percentages and are compared using the Chi2 test. The quantitative variables are expressed as mean ± standard deviation and compared using Student's T-test. Statistical significance p <0.05. RESULTS: 38 patients, mean age 66 ± 18 years, 51.4% men. 92.1% had arterial hypertension, 39.5% diabetes mellitus (DM). 63.2% on hemodialysis, 2.6% peritoneal dialysis, 34.2% transplanted. 84.2% presented fever, 63.2% cough, 73.7% pneumonia, 34.2% dyspnea, 15.8% digestive symptoms. 21.1% leukopenia, 73.7% lymphopenia, money D 1509 ± 1351, CRP 12.45 ± 19.47, sodium 136 ± 5.5. 81.% were admitted to hospitalization, of which 2.6% required admission to the ICU. 44% died. Mortality was statistically significantly related to DM (56.3% vs 43.8% p = 0.05), and with the need for hospitalization (93.8 vs 6.3% p = 0.054). CONCLUSION: In our experience, DM patients and those who required hospitalization had a higher risk of mortality.