Author: Luca Carsana; Aurelio Sonzogni; Ahmed Nasr; Roberta Rossi; Alessandro Pellegrinelli; Pietro Zerbi; Roberto Rech; Riccardo Colombo; Spinello Antinori; Mario Corbellino; Massimo Galli; Emanuele Catena; Antonella Tosoni; Andrea Gianatti; Manuela Nebuloni
Title: Pulmonary post-mortem findings in a large series of COVID-19 cases from Northern Italy Document date: 2020_4_22
ID: 8pkwqg5j_21
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.19.20054262 doi: medRxiv preprint 6 Finally, the search for viral particles was carried out in a subset of patients and highlighted the presence of rare virions in the cytoplasm of pneumocytes. Despite the low number of cases, these findings may suggest that the virus remains in lung tissue for many days, even if in small quantities, poss.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.19.20054262 doi: medRxiv preprint 6 Finally, the search for viral particles was carried out in a subset of patients and highlighted the presence of rare virions in the cytoplasm of pneumocytes. Despite the low number of cases, these findings may suggest that the virus remains in lung tissue for many days, even if in small quantities, possibly being the trigger of the mechanism that leads to and feeds lung damage. Further histological and molecular analyses and extension of the series are ongoing to better define cellular and tissue distribution of viruses and organ inflammatory response.
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