Author: Saba Ismail; Sajjad Ahmad; Syed Sikander Azam
Title: Immuno-informatics Characterization SARS-CoV-2 Spike Glycoprotein for Prioritization of Epitope based Multivalent Peptide Vaccine Document date: 2020_4_12
ID: 3jmo35jc_26
Snippet: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.05.026005 doi: bioRxiv preprint 30 hours, yeast, in vivo is greater than 20 hours, and Escherichia coli, in vivo higher than 10 hours. The antigenicity of the MEPVC was cross-checked and predicted highly antigenic with value of 0.69. Total entropy of the protein is 17.0170 which is considered ideal and also the vaccine has no transmembran.....
Document: The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.04.05.026005 doi: bioRxiv preprint 30 hours, yeast, in vivo is greater than 20 hours, and Escherichia coli, in vivo higher than 10 hours. The antigenicity of the MEPVC was cross-checked and predicted highly antigenic with value of 0.69. Total entropy of the protein is 17.0170 which is considered ideal and also the vaccine has no transmembrane helices (alpha helical transmembrane protein, 0.0474783 and beta barrel transmembrane protein, 0.0060384) hence no difficulties can be anticipated in cloning and expression analysis. The predicted solubility upon overexpression of MEPVC is 0.965751 reflecting higher solubility of MEPVC.
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