Author: Ashutosh Kumar; Muneeb A. Faiq; Vikas Pareek; Khursheed Raza; Ravi K. Narayan; Pranav Prasoon; Pavan Kumar; Maheswari Kulandhasamy; Chiman Kumari; Kamla Kant; Himanshu N. Singh; Rizwana Qadri; Sada N. Pandey; Santosh Kumar
Title: Relevance of enriched expression of SARS-CoV-2 binding receptor ACE2 in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients Document date: 2020_4_15
ID: gpzyiuo7_13
Snippet: We analyzed the tissue specific distribution of ACE2 receptor expression (mRNA and protein) in digestive system components (GIT, liver & GB, and pancreas) using RNA sequencing and immunohistochemistry (IHC) data available in Human Protein Atlas (https://www.proteinatlas.org/search/ACE2). A digestive system specific functional enrichment map of ACE2 gene was constructed using g:profiler (https://biit.cs.ut.ee/gprofiler/gost) utility and viewed wit.....
Document: We analyzed the tissue specific distribution of ACE2 receptor expression (mRNA and protein) in digestive system components (GIT, liver & GB, and pancreas) using RNA sequencing and immunohistochemistry (IHC) data available in Human Protein Atlas (https://www.proteinatlas.org/search/ACE2). A digestive system specific functional enrichment map of ACE2 gene was constructed using g:profiler (https://biit.cs.ut.ee/gprofiler/gost) utility and viewed with Cytoscape software, version 3.7.2 (https://cytoscape.org/).
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