Selected article for: "SARS cov and sequence analysis"

Author: Ramya Rangan; Ivan N. Zheludev; Rhiju Das
Title: RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses
  • Document date: 2020_3_28
  • ID: kjeqdse5_1_1
    Snippet: ing on conservation and structure patterns most relevant to the current pandemic, we chose to analyze not all betacoronaviruses but a subgroup of SARS-related betacoronaviruses. These include SARS, SARS-CoV-2, and SARS-related bat coronaviruses, but not MERS, MHV, or other betacoronaviruses which have been classified into distinct subgroups based on different sequence and structure features in, for example, their 5´ UTR's. 9 We carried out this .....
    Document: ing on conservation and structure patterns most relevant to the current pandemic, we chose to analyze not all betacoronaviruses but a subgroup of SARS-related betacoronaviruses. These include SARS, SARS-CoV-2, and SARS-related bat coronaviruses, but not MERS, MHV, or other betacoronaviruses which have been classified into distinct subgroups based on different sequence and structure features in, for example, their 5´ UTR's. 9 We carried out this analysis beginning with three different sequence alignments. Each captures a range of complete genome sequences across the SARS-related betacoronviruses, but differ in the total number of sequences and in the redundancy of those sequences, as follows:

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