Selected article for: "cov infection and infection control"
Author: Hualong Xiong; Yangtao Wu; Jiali Cao; Ren Yang; Jian Ma; Xiaoyang Qiao; Xiangyang Yao; Baohui Zhang; Yali Zhang; Wangheng Hou; Yang Shi; Jingjing Xu; Liang Zhang; Shaojuan Wang; Baorong Fu; Ting Yang; Shengxiang Ge; Jun Zhang; Quan Yuan; Baoying Huang; Zhiyong Li; Tianying Zhang; Ningshao Xia
Title: Robust neutralization assay based on SARS-CoV-2 S-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressed BHK21 cells
  • Document date: 2020_4_9
    • ID: fvjh3g7v_1
    Snippet: As of April 5, 2020, over 1.2 million cases of coronavirus disease 2019 (COVID-19) have been reported, including 68,000 deaths. The spread of the SARS-CoV-2 virus is difficult to control due to the highly contagious and asymptomatic infection. There is an urgent need to develop vaccines or therapeutics against SARS-CoV-2 infection. However, SARS-CoV-2 culture and assays need to be carried out in biosafety level-3 laboratory, which limits the effi.....
    Document: As of April 5, 2020, over 1.2 million cases of coronavirus disease 2019 (COVID-19) have been reported, including 68,000 deaths. The spread of the SARS-CoV-2 virus is difficult to control due to the highly contagious and asymptomatic infection. There is an urgent need to develop vaccines or therapeutics against SARS-CoV-2 infection. However, SARS-CoV-2 culture and assays need to be carried out in biosafety level-3 laboratory, which limits the efficiency of research and development (R & D). Widely available and convenient functional assays, such as cell-based assays for neutralizing quantification, are essential for vaccine and therapeutic antibody R & D [1] [2] [3] .

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