Selected article for: "avian influenza and syncytial virus"
Author: Hudson, James; Vimalanathan, Selvarani
Title: Echinacea—A Source of Potent Antivirals for Respiratory Virus Infections
  • Cord-id: osdkejhz
  • Document date: 2011_7_13
    • ID: osdkejhz
    Snippet: Extracts of Echinacea species have been used traditionally in North America for the control of symptoms of colds, influenza, and other diseases, and some of them have become very popular as “herbal medicines”. Recent studies have revealed that preparations derived from certain species and plant parts, but not all of them, possess potent antiviral activities, at non-cytotoxic concentrations, particularly against membrane-containing viruses. Thus all strains of human and avian influenza viruse
    Document: Extracts of Echinacea species have been used traditionally in North America for the control of symptoms of colds, influenza, and other diseases, and some of them have become very popular as “herbal medicines”. Recent studies have revealed that preparations derived from certain species and plant parts, but not all of them, possess potent antiviral activities, at non-cytotoxic concentrations, particularly against membrane-containing viruses. Thus all strains of human and avian influenza viruses tested (including a Tamiflu-resistant strain), as well as herpes simplex virus, respiratory syncytial virus, and rhinoviruses, were very sensitive to a standardized Echinacea purpurea preparation. In mechanistic studies the influenza virus-specific hemagglutinin and neuraminidase were inhibited. In addition some extracts displayed anti-inflammatory activity in virus-infected cells, and numerous other effects on the expression of cellular genes. Multiple components, either discrete compounds or mixtures, appeared to be responsible for the various antiviral activities.

    Search related documents:
    Co phrase search for related documents
    • absence presence and activation status: 1
    • absence presence and activity responsible: 1, 2
    • absence presence and acute respiratory syndrome: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, 50, 51, 52, 53, 54, 55, 56, 57, 58, 59, 60, 61, 62, 63, 64, 65, 66, 67, 68, 69, 70, 71, 72
    • absence presence and adaptive immune response: 1, 2
    • absence presence and addition provide: 1
    • absence presence and addition rhinovirus: 1
    • absence presence and additional benefit: 1, 2
    • absence presence and additional experiment: 1, 2
    • absence presence and adenovirus type: 1, 2, 3
    • absence presence and low respiratory: 1
    • absence presence and lung bronchial: 1, 2, 3
    • accordingly pharmaceutical and acute respiratory syndrome: 1
    • acetate fraction and activity responsible: 1