Author: Seitz, Tamara; Schindler, Stefanie; Winkelmeyer, Patrick; Zach, Bernhard; Wenisch, Christoph; Zoufaly, Alexander; Allerberger, Franz
Title: Evaluation of rapid antigen tests based on saliva for the detection of SARSâ€CoVâ€2 Cord-id: tr6g357x Document date: 2021_4_13
ID: tr6g357x
Snippet: Rapid identification and isolation of with SARS-CoV-2 infected individuals is crucial. Recent studies have shown that RT-PCR from self-collected saliva is a suitable alternative to nasopharyngeal swab. A disadvantage of RT-PCR resulting in a long time until result which may be problematic. To address this problem, in this study a rapid antigen testCE-certified for the detection of SARS-CoV-2 using saliva (COVID-19 Antigen Test Cassette (hypersensitive colloidal gold) was evaluated. An overall se
Document: Rapid identification and isolation of with SARS-CoV-2 infected individuals is crucial. Recent studies have shown that RT-PCR from self-collected saliva is a suitable alternative to nasopharyngeal swab. A disadvantage of RT-PCR resulting in a long time until result which may be problematic. To address this problem, in this study a rapid antigen testCE-certified for the detection of SARS-CoV-2 using saliva (COVID-19 Antigen Test Cassette (hypersensitive colloidal gold) was evaluated. An overall sensitivity of saliva rapid antigen test of 44.4% and a specificity of 100% compared with RT-PCR-results from gargle solution as gold standard was shown. The data suggests that rapid antigen tests based on saliva for the detection of SARS-CoV-2 are not a no reliable substitute for RT-PCR. This article is protected by copyright. All rights reserved.
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