Selected article for: "age distribution and disease onset date"
Author: Julien Riou; Anthony Hauser; Michel J Counotte; Christian L Althaus
Title: Adjusted age-specific case fatality ratio during the COVID-19 epidemic in Hubei, China, January and February 2020
  • Document date: 2020_3_6
    • ID: mrsya6wz_39
    Snippet: Observing such similar estimates in very different settings may be an indication of some degree of generalizability. However, direct extrapolation of these estimates to other countries must be done with caution, as the pattern of an epidemic, the standard of care and, as a result, mortality are time-and setting-dependent. For instance, very few deaths have been reported so far in South Korea [33] . In this country, there is a large excess of youn.....
    Document: Observing such similar estimates in very different settings may be an indication of some degree of generalizability. However, direct extrapolation of these estimates to other countries must be done with caution, as the pattern of an epidemic, the standard of care and, as a result, mortality are time-and setting-dependent. For instance, very few deaths have been reported so far in South Korea [33] . In this country, there is a large excess of young women in a cluster of SARS-CoV-2 infections associated with the Shincheonji Church of Jesus [34] . The higher number of young people among cases, widespread testing and better management of the epidemic might explain the fewer numbers of reported fatalities. The disproportionate influence of this cluster on the age-specific distribution of cases prevented us from applying the same model based on the age distributions in the general population. Data from other countries, in particular the number of cases by date of disease onset and the age and gender distribution of cases and deaths, are necessary to better understand the variability in mortality across settings.

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