Selected article for: "expected number and international license"
Author: Ramya Rangan; Ivan N. Zheludev; Rhiju Das
Title: RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses
  • Document date: 2020_3_28
    • ID: kjeqdse5_33
    Snippet: . CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.27.012906 doi: bioRxiv preprint MEA structures were computed using Contrafold 2.0 18 for 20 nucleotide flanking windows around conserved intervals in SARS-CoV-2. To estimate the Matthews correlation coefficient of these single-structure predictions, we computed .....
    Document: . CC-BY 4.0 International license author/funder. It is made available under a The copyright holder for this preprint (which was not peer-reviewed) is the . https://doi.org/10.1101/2020.03.27.012906 doi: bioRxiv preprint MEA structures were computed using Contrafold 2.0 18 for 20 nucleotide flanking windows around conserved intervals in SARS-CoV-2. To estimate the Matthews correlation coefficient of these single-structure predictions, we computed the pseudo-expected Matthews correlation coefficient as described in Hamada, et al. 19 Base-pairing probability matrices were computed Contrafold 2.0, and these were then used to calculated the expected number of true positive, true negative, false positive, and false negative base pairs. These computations were carried out using the Arnie package (https://github.com/DasLab/arnie).

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