Author: Sangtani, Rimjhim; Ghosh, Atreyee; Jha, Hem C.; Parmar, Hamendra Singh; Bala, Kiran
Title: Potential of algal metabolites for the development of broadâ€spectrum antiviral therapeutics: Possible implications in COVIDâ€19 therapy Cord-id: xe2rrpdv Document date: 2020_11_18
ID: xe2rrpdv
Snippet: Covidâ€19 pandemic severely affected human health worldwide. Till October 19, 2020, total confirmed patients of COVIDâ€19 are 39,944,882, whereas 1,111,998 people died across the globe. Till to date, we do not have any specific medicine and/or vaccine to treat COVIDâ€19; however, research is still going on at war footing. So far vaccine development is concerned, here it is noteworthy that till now three major variants (named A, B, and C) of severe acute respiratory syndromeâ€coronavirus2 (SA
Document: Covidâ€19 pandemic severely affected human health worldwide. Till October 19, 2020, total confirmed patients of COVIDâ€19 are 39,944,882, whereas 1,111,998 people died across the globe. Till to date, we do not have any specific medicine and/or vaccine to treat COVIDâ€19; however, research is still going on at war footing. So far vaccine development is concerned, here it is noteworthy that till now three major variants (named A, B, and C) of severe acute respiratory syndromeâ€coronavirus2 (SARSâ€CoVâ€2) have been recognized. Increased mutational rate and formation of new viral variants may increase the attrition rate of vaccines and/or candidate chemotherapies. Herbal remedies are chemical cocktails, thus open another avenue for effective antiviral therapeutics development. In fact, India is a large country, which is densely populated, but the overall severity of COVIDâ€19 per million populations is lesser than any other country of the world. One of the major reasons for the aforesaid difference is the use of herbal remedies by the Government of India as a preventive measure for COVIDâ€19. Therefore, the present review focuses on the epidemiology and molecular pathogenesis of COVIDâ€19 and explores algal metabolites for their antiviral properties.
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