Author: Gerevini, Simonetta; Napolitano, Angela; Cava, Mariangela; Giazzi, Emilio; Agostinis, Cristina
Title: Possible Thrombotic Microangiopathy Occurring in Patient with CNS Localization of SARS-Cov-2 Cord-id: wbqhjmjl Document date: 2021_3_18
ID: wbqhjmjl
Snippet: It is well documented that SARS-CoV-2 can cause damage to endothelial cells in the lungs, the heart, and the kidneys, activating inflammatory and thrombotic pathways [1]. Endothelial cell infection or monocyte activation, upregulation of tissue factors, and the release of microparticles, which activate the thrombotic pathway and cause microangiopathy, might occur for SARS-CoV-2 as for other viruses [2].
Document: It is well documented that SARS-CoV-2 can cause damage to endothelial cells in the lungs, the heart, and the kidneys, activating inflammatory and thrombotic pathways [1]. Endothelial cell infection or monocyte activation, upregulation of tissue factors, and the release of microparticles, which activate the thrombotic pathway and cause microangiopathy, might occur for SARS-CoV-2 as for other viruses [2].
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