Author: Renfei Lu; Jian Wang; Min Li; Yaqi Wang; Jia Dong; Weihua Cai
Title: SARS-CoV-2 detection using digital PCR for COVID-19 diagnosis, treatment monitoring and criteria for discharge Document date: 2020_3_30
ID: mskkahwi_10
Snippet: Results from dPCR targeting ORF1ab gene were also consistent with that from RT-PCR result (Table 144 4). In particular, 4 positive samples from 3 patients based on dPCR assay were not detected by PCR. The computerized tomography (CT) results of the 3 patients showed 1 patient's lung texture 146 thickening, no pneumonia imaging characteristics; 1 patient had two lungs infections,; and 1 patient 147 showed inflammation of the right lung and lower .....
Document: Results from dPCR targeting ORF1ab gene were also consistent with that from RT-PCR result (Table 144 4). In particular, 4 positive samples from 3 patients based on dPCR assay were not detected by PCR. The computerized tomography (CT) results of the 3 patients showed 1 patient's lung texture 146 thickening, no pneumonia imaging characteristics; 1 patient had two lungs infections,; and 1 patient 147 showed inflammation of the right lung and lower lobe. But RT-PCR assay failed to detect these 4 148 samples, and generated negative results. 149
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