Author: Jennifer C.E Lane; James Weaver; Kristin Kostka; Talita Duarte-Salles; Maria Tereza F. Abrahao; Heba Alghoul; Osaid Alser; Thamir M Alshammari; Patricia Biedermann; Edward Burn; Paula Casajust; Mitch Conover; Aedin C. Culhane; Alexander Davydov; Scott L. DuVall; Dmitry Dymshyts; Sergio Fernández Bertolín; Kristina Fišter; Jill Hardin; Laura Hester; George Hripcsak; Seamus Kent; Sajan Khosla; Spyros Kolovos; Christophe G. Lambert; Johan ver der Lei; Ajit A. Londhe; Kristine E. Lynch; Rupa Makadia; Andrea V. Margulis; Michael E. Matheny; Paras Mehta; Daniel R. Morales; Henry Morgan-Stewart; Mees Mosseveld; Danielle Newby; Fredrik Nyberg; Anna Ostropolets; Rae Woong Park; Albert Prats-Uribe; Gowtham A. Rao; Christian Reich; Jenna Reps; Peter Rijnbeek; Selva Muthu Kumaran Sathappan; Martijn Schuemie; Sarah Seager; Anthony Sena; Azza Shoaibi; Matthew Spotnitz; Marc A. Suchard; Joel Swerdel; Carmen Olga Torre; David Vizcaya; Haini Wen; Marcel de Wilde; Seng Chan You; Lin Zhang; Oleg Zhuk; Patrick Ryan; Daniel Prieto-Alhambra
Title: Safety of hydroxychloroquine, alone and in combination with azithromycin, in light of rapid wide-spread use for COVID-19: a multinational, network cohort and self-controlled case series study Document date: 2020_4_10
ID: 2hbcbvt6_66
Snippet: A systematic review of the cardiac side effects of chloroquine and HCQ identified 86 articles reporting short series or individual cases. 39 In the 127 included patients, cardiac side effects occurred in mainly women (65.4%) who had a median age of 56 years. Conduction disorders were the main side effect reported (85%), with heart failure (26.8%), ventricular hypertrophy (22%), hypokinesia (9.4%), valvular dysfunction (7.1%) and pulmonary arteria.....
Document: A systematic review of the cardiac side effects of chloroquine and HCQ identified 86 articles reporting short series or individual cases. 39 In the 127 included patients, cardiac side effects occurred in mainly women (65.4%) who had a median age of 56 years. Conduction disorders were the main side effect reported (85%), with heart failure (26.8%), ventricular hypertrophy (22%), hypokinesia (9.4%), valvular dysfunction (7.1%) and pulmonary arterial hypertension (3.9%) being the other reported side effects.
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