Author: Ke Wang; Wei Chen; Yu-Sen Zhou; Jian-Qi Lian; Zheng Zhang; Peng Du; Li Gong; Yang Zhang; Hong-Yong Cui; Jie-Jie Geng; Bin Wang; Xiu-Xuan Sun; Chun-Fu Wang; Xu Yang; Peng Lin; Yong-Qiang Deng; Ding Wei; Xiang-Min Yang; Yu-Meng Zhu; Kui Zhang; Zhao-Hui Zheng; Jin-Lin Miao; Ting Guo; Ying Shi; Jun Zhang; Ling Fu; Qing-Yi Wang; Huijie Bian; Ping Zhu; Zhi-Nan Chen
Title: SARS-CoV-2 invades host cells via a novel route: CD147-spike protein Document date: 2020_3_14
ID: 5hpbjkft_4
Snippet: CD147, also known as Basigin or EMMPRIN, is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily [9] , which is involved in tumor development, plasmodium invasion and virus infection [10] [11] [12] [13] [14] [15] [16] . Our previous researches show that CD147 plays a functional role in facilitating SARS-CoV invasion for host cells, and CD147-antagonistic peptide-9 has a high binding rate to HEK293 cells and an inhibitory ef.....
Document: CD147, also known as Basigin or EMMPRIN, is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily [9] , which is involved in tumor development, plasmodium invasion and virus infection [10] [11] [12] [13] [14] [15] [16] . Our previous researches show that CD147 plays a functional role in facilitating SARS-CoV invasion for host cells, and CD147-antagonistic peptide-9 has a high binding rate to HEK293 cells and an inhibitory effect on SARS-CoV [16] . These researches affirm the importance of CD147 in virus invasion for host cells. Owing to the similar characteristics of SARS-CoV and SARS-CoV-2, we conduct the present study to investigate the possible function of CD147 in invasion for host cells by SARS-CoV-2.
Search related documents:
Co phrase search for related documents- binding rate and host cell: 1, 2, 3, 4, 5, 6
- binding rate and inhibitory effect: 1
- binding rate and present study: 1
- binding rate and SARS cov: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- binding rate and SARS cov invasion: 1
- binding rate and transmembrane glycoprotein: 1
- functional role and host cell: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20
- functional role and inhibitory effect: 1, 2
- functional role and present study: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21
- functional role and previous research: 1, 2, 3
- functional role and SARS cov: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25
- functional role and SARS cov invasion: 1, 2
- functional role and tumor development: 1, 2
- host cell and SARS cov invasion: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23
- host cell and similar characteristic: 1
- host cell and superfamily immunoglobulin: 1, 2, 3, 4
- host cell and transmembrane glycoprotein: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22
- host cell and tumor development: 1
- host cell and virus invasion: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12
Co phrase search for related documents, hyperlinks ordered by date