Author: Shen Xu; Lin Fu; Jun Fei; Hui-Xian Xiang; Ying Xiang; Zhu-Xia Tan; Meng-Die Li; Fang-Fang Liu; Ying Li; Ming-Feng Han; Xiu-Yong Li; De-Xin Yu; Hui Zhao; De-Xiang Xu
Title: Acute kidney injury at early stage as a negative prognostic indicator of patients with COVID-19: a hospital-based retrospective analysis Document date: 2020_3_26
ID: b4ay5vyp_30
Snippet: The mechanism by which SARS-CoV-2 injection induces AKI is likely to be multifactorial. Several reports showed that most COVID-19 patients were companied with multiple organ damage 9, 14 . However, the present study found that there was no significant association between oxygenation index and all measured renal functional indices among COVID-19 patients with AKI, suggesting that SARS-CoV-2-induced AKI is independent of respiratory failure. Two ea.....
Document: The mechanism by which SARS-CoV-2 injection induces AKI is likely to be multifactorial. Several reports showed that most COVID-19 patients were companied with multiple organ damage 9, 14 . However, the present study found that there was no significant association between oxygenation index and all measured renal functional indices among COVID-19 patients with AKI, suggesting that SARS-CoV-2-induced AKI is independent of respiratory failure. Two early reports showed that ACE2, as a receptor for SARS-CoV-2, was highly expressed in renal tubular epithelium 18, 19 .
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