Author: Naoto Hori; Natalia A. Denesyuk; D. Thirumalai
Title: Salt Effects on the Thermodynamics of a Frameshifting RNA Pseudoknot under Tension Document date: 2016_4_15
ID: 08mep8hm_30
Snippet: where C 0 is an arbitrary reference value of the salt concentration [45] . Note that we consider only 1:1 monovalent salt such as KCl or NaCl for which ion activity can be related to salt concentration C. The factor of 2 in Eq. (1) arises from charge neutrality. The difference, ∆Γ αβ (=Γ β −Γ α ), is interpreted as an effective number of bound or excluded ions when the RNA molecule changes its conformation between the two states [35, 4.....
Document: where C 0 is an arbitrary reference value of the salt concentration [45] . Note that we consider only 1:1 monovalent salt such as KCl or NaCl for which ion activity can be related to salt concentration C. The factor of 2 in Eq. (1) arises from charge neutrality. The difference, ∆Γ αβ (=Γ β −Γ α ), is interpreted as an effective number of bound or excluded ions when the RNA molecule changes its conformation between the two states [35, 44] . The free energy change upon application of an external force f is ∆G αβ (f ) = ∆G αβ (0)+∆R αβ ee ·f where ∆R αβ ee = R α ee −R β ee [29] . Thus,
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