Selected article for: "mechanical force and RNA stability"
Author: Naoto Hori; Natalia A. Denesyuk; D. Thirumalai
Title: Salt Effects on the Thermodynamics of a Frameshifting RNA Pseudoknot under Tension
  • Document date: 2016_4_15
    • ID: 08mep8hm_4
    Snippet: variations in the frameshift efficiency, which, for some mutants, is attributed to changes in the stem-loop interactions affecting the stability of PK. For others, direct involvement of the ribosome is invoked [25] . In addition to mechanical force (f ), it is known from several ensemble experiments that the stability of BWYV PK, like other RNA molecules, depends on monovalent and divalent cations [33] . Thus, it is important to understand in qua.....
    Document: variations in the frameshift efficiency, which, for some mutants, is attributed to changes in the stem-loop interactions affecting the stability of PK. For others, direct involvement of the ribosome is invoked [25] . In addition to mechanical force (f ), it is known from several ensemble experiments that the stability of BWYV PK, like other RNA molecules, depends on monovalent and divalent cations [33] . Thus, it is important to understand in quantitative detail how this crucial structural motif respond to f and changes in ion concentration.

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