Author: Jun Fei; Lin Fu; Ying Li; Hui-Xian Xiang; Ying Xiang; Meng-Die Li; Fang-Fang Liu; De-xiang Xu; Hui Zhao
Title: Reduction of lymphocyte at early stage elevates severity and death risk of COVID-19 patients: a hospital-based case-cohort study Document date: 2020_4_6
ID: 8q1veo3q_3
Snippet: The clinical symptoms and features of COVID-19 patients include fever, dry cough, bilateral lung ground glass opacity, dyspnea and diarrhea. In severe and critical ill cases, SARS-CoV-2-caused pneumonia leads to not only severe acute respiratory syndrome but also multiple organ failure even death (6) . Furthermore, several studies found that lymphocyte count from peripheral blood was decreased in most patients with COVID-19. Lymphocyte count in s.....
Document: The clinical symptoms and features of COVID-19 patients include fever, dry cough, bilateral lung ground glass opacity, dyspnea and diarrhea. In severe and critical ill cases, SARS-CoV-2-caused pneumonia leads to not only severe acute respiratory syndrome but also multiple organ failure even death (6) . Furthermore, several studies found that lymphocyte count from peripheral blood was decreased in most patients with COVID-19. Lymphocyte count in severe patients was obviously lower than that of common patients (1, 6, 7) . Nevertheless, what factors lead to lymphopenia remains unclear. The association between lymphocyte reduction and the prognosis of COVID-19 patients needs to be determined.
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