Selected article for: "genome sequence and reference sequence"
Author: Ramya Rangan; Ivan N. Zheludev; Rhiju Das
Title: RNA genome conservation and secondary structure in SARS-CoV-2 and SARS-related viruses
  • Document date: 2020_3_28
    • ID: kjeqdse5_4
    Snippet: In Fig. 2 , we depict conserved regions (100% conservation cutoff, SARSr-MSA-1) alongside the genome coordinates for the reference SARS-CoV-2 sequence. We observe intervals of conservation in the 5´ UTR and 3´ UTR genome regions, as expected based on prior work demonstrating sequence conservation surrounding structured RNA elements in these regions, 13 but we also noted stretches of RNA sequence conservation within some viral ORFs......
    Document: In Fig. 2 , we depict conserved regions (100% conservation cutoff, SARSr-MSA-1) alongside the genome coordinates for the reference SARS-CoV-2 sequence. We observe intervals of conservation in the 5´ UTR and 3´ UTR genome regions, as expected based on prior work demonstrating sequence conservation surrounding structured RNA elements in these regions, 13 but we also noted stretches of RNA sequence conservation within some viral ORFs.

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