Author: Grint, D. J.; Wing, K.; Williamson, E.; McDonald, H. I.; Bhaskaran, K.; Evans, D.; Evans, S. J.; Walker, A. J.; Hickman, G.; Nightingale, E.; Schultze, A.; Rentsch, C. T.; Bates, C.; Cockburn, J.; Curtis, H. J.; Morton, C. E.; Bacon, S.; Davy, S.; Wong, A. Y.; Mehrkar, A.; Tomlinson, L.; Douglas, I. J.; Mathur, R.; Blomquist, P.; McKenna, B.; Ingelsby, P.; Croker, R.; Parry, J.; Hester, F.; Harper, S.; DeVito, N. J.; Hulme, W.; Tazare, J.; Goldacre, B.; Smeeth, L.; Eggo, R. M.
Title: Case fatality risk of the SARS-CoV-2 variant of concern B.1.1.7 in England Cord-id: q4q06pzc Document date: 2021_3_8
ID: q4q06pzc
Snippet: The B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is critical for pandemic planning. We found increased risk of death for VOC compared with non-VOC cases in England (HR: 1.67 (95% CI: 1.34 - 2.09; P<.0001). Absolute risk of death by 28-days increased with age and comorbidities. VOC has potential to spread faster with higher mortality than the pandemic to date.
Document: The B.1.1.7 variant of concern (VOC) is increasing in prevalence across Europe. Accurate estimation of disease severity associated with this VOC is critical for pandemic planning. We found increased risk of death for VOC compared with non-VOC cases in England (HR: 1.67 (95% CI: 1.34 - 2.09; P<.0001). Absolute risk of death by 28-days increased with age and comorbidities. VOC has potential to spread faster with higher mortality than the pandemic to date.
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