Author: Salinas-Botrán, A.; Sanz-Cánovas, J.; Pérez-Somarriba, J.; Pérez-Belmonte, L.M.; Cobos-Palacios, L.; Rubio-Rivas, M.; de-CossÃo-Tejido, S.; Ramos-Rincón, J.M.; Méndez-Bailón, M.; Gómez-Huelgas, R.
Title: Clinical characteristics and risk factors for mortality upon admission in patients with heart failure hospitalized due to COVID-19 in Spain() Cord-id: x764rxb9 Document date: 2021_10_8
ID: x764rxb9
Snippet: BACKGROUND: There are few studies on patients with heart failure (HF) hospitalized for COVID-19. Our aim is to describe the clinical characteristics of patients with HF hospitalized for COVID-19 and identify risk factors for in-hospital mortality upon admission. METHODS: We conducted a retrospective, multicenter study in patients with HF hospitalized for COVID-19 in 150 Spanish hospitals (SEMI-COVID-19 Registry). A multivariate logistic regression analysis was performed to identify admission fac
Document: BACKGROUND: There are few studies on patients with heart failure (HF) hospitalized for COVID-19. Our aim is to describe the clinical characteristics of patients with HF hospitalized for COVID-19 and identify risk factors for in-hospital mortality upon admission. METHODS: We conducted a retrospective, multicenter study in patients with HF hospitalized for COVID-19 in 150 Spanish hospitals (SEMI-COVID-19 Registry). A multivariate logistic regression analysis was performed to identify admission factors associated with in-hospital mortality. RESULTS: A total of 1718 patients were analyzed (56.5% men; median age 81.4 years). The overall case fatality rate was 47.6% (n = 819). The independent risk factors at admission for in-hospital mortality were: age (adjusted odds ratio [AOR]: 1.03; 95% confidence interval [95%CI]: 1.02–1.05; p < .001); severe dependence (AOR: 1.62; 95%CI: 1.19–2.20; p = .002); tachycardia (AOR: 1.01; 95%CI: 1.00–1.01; p = .004); and high C-reactive protein (AOR: 1.004; 95%CI:1.002−1.004; p < .001), LDH (AOR: 1.001; 95%CI: 1.001−1.002; p < .001), and serum creatinine levels (AOR: 1.35; 95%CI: 1.18−1.54; p < .001). CONCLUSIONS: Patients with HF hospitalized for COVID-19 have a high in-hospital mortality rate. Some simple clinical and laboratory tests can help to identify patients with a worse prognosis.
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