Author: Ashutosh Kumar; Muneeb A. Faiq; Vikas Pareek; Khursheed Raza; Ravi K. Narayan; Pranav Prasoon; Pavan Kumar; Maheswari Kulandhasamy; Chiman Kumari; Kamla Kant; Himanshu N. Singh; Rizwana Qadri; Sada N. Pandey; Santosh Kumar
Title: Relevance of enriched expression of SARS-CoV-2 binding receptor ACE2 in gastrointestinal tissue with pathogenesis of digestive symptoms, diabetes-associated mortality, and disease recurrence in COVID-19 patients Document date: 2020_4_15
ID: gpzyiuo7_26
Snippet: High expression of ACE2 in glandular cells of the GB indicates that this also can be a potential site for the virus replication. GB has a luminal connection to the duodenum through cystic and common bile duct (CBD). Though this connection is guarded by a sphincter (of Oddi) present in duodenal mucosa, it doesn't create an anatomical barrier and, therefore, a viral invasion along the mucosal epithelium remains a possibility......
Document: High expression of ACE2 in glandular cells of the GB indicates that this also can be a potential site for the virus replication. GB has a luminal connection to the duodenum through cystic and common bile duct (CBD). Though this connection is guarded by a sphincter (of Oddi) present in duodenal mucosa, it doesn't create an anatomical barrier and, therefore, a viral invasion along the mucosal epithelium remains a possibility.
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