The breadth of concomitant virological features in a family cluster outbreak of COVID‐19 pneumonia

Lei, Guanglin; Meng, Fanping; Wang, Cheng; Yan, Jin; Sun, Fang; Shi, Lei; Li, Wengang; Luan, Junqing; Wang, Siyu; Yang, Penghui

An outbreak of a novel coronavirus disease (COVID‐19) caused by severe acute respiratory syndrome coronavirus 2 (SARS‐CoV‐2) had emerged in 2019 and rapidly posed a global epidemic. Here, we report the breadth of concomitant virological features of a family cluster with COVID‐19. The period of virus shedding is significantly different between upper respiratory and feces samples. Even the SARS‐CoV‐2 virus titers were undetectable in feces, it could be positive again soon and likely related to fluctuated inflammation levels (interleukin‐6, etc.) and lowered immune responses (CD4 + T lymphocyte, etc.). Our findings expand the novel understanding of the breadth of concomitant virological features during a non‐severe family cluster of COVID‐19.