Author: Hualong Xiong; Yangtao Wu; Jiali Cao; Ren Yang; Jian Ma; Xiaoyang Qiao; Xiangyang Yao; Baohui Zhang; Yali Zhang; Wangheng Hou; Yang Shi; Jingjing Xu; Liang Zhang; Shaojuan Wang; Baorong Fu; Ting Yang; Shengxiang Ge; Jun Zhang; Quan Yuan; Baoying Huang; Zhiyong Li; Tianying Zhang; Ningshao Xia
Title: Robust neutralization assay based on SARS-CoV-2 S-bearing vesicular stomatitis virus (VSV) pseudovirus and ACE2-overexpressed BHK21 cells Document date: 2020_4_9
ID: fvjh3g7v_23
Snippet: Among the 18 tested sera, 5 of them show high neutralizing activity (ID 50 >1000). Similar assay was also performed using live SARS-CoV-2 system. 7 sera show high neutralizing activity (ID 50 >1000) according to live virus assay ( Figure 6B ). The analysis result of the pseudovirus system correlates well with live virus system (R 2 =0.639, P<0.0001, Figure 6C )......
Document: Among the 18 tested sera, 5 of them show high neutralizing activity (ID 50 >1000). Similar assay was also performed using live SARS-CoV-2 system. 7 sera show high neutralizing activity (ID 50 >1000) according to live virus assay ( Figure 6B ). The analysis result of the pseudovirus system correlates well with live virus system (R 2 =0.639, P<0.0001, Figure 6C ).
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